"There is nothing new to be discovered in physics now" was supposedly a common refrain among late-Victorian scientists – shortly before quantum theory and Einstein’s relativity overturned everything.
Last year’s discovery of the Higgs boson capped decades of sculpting quantum theory into the standard model of particle physics – yet it, too, is found wanting. Meanwhile, melding the two pillars of 20th-century physics into one "theory of everything" remains a dream.
It may once again be time for a radical rethink, starting with the most fundamental question of all…
What makes us so sure that mathematics can reveal nature's deepest workings, asks cosmologist